Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota

Highlights

  • Intermittent Fasting (IF) ameliorates the clinical course and pathology of the MS mouse model (EAE)
  • IF increases gut microbial diversity, alters their composition and metabolic pathways
  • Gut microbiota transfer from mice on IF led to protection from EAE in recipient mice
  • Findings with IER in MS patients partially recapitulates what is observed with IF in EAE

A new paper in the journal Cell Metabolism shows that intermittent fasting (IF) can improve symptoms of multiple sclerosis, and that the effects are likely due to changes in the gut microbiota.  George Weinstock and Yanjiao Zhou of The Jackson Laboratory were among the microbiome experts involved in the research.

News Reports

Can fasting improve MS symptoms?  Medical Express

Intermittent fasting may benefit people with MS  Medical News Today