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Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota

Highlights

  • Intermittent Fasting (IF) ameliorates the clinical course and pathology of the MS mouse model (EAE)
  • IF increases gut microbial diversity, alters their composition and metabolic pathways
  • Gut microbiota transfer from mice on IF led to protection from EAE in recipient mice
  • Findings with IER in MS patients partially recapitulates what is observed with IF in EAE

A new paper in the journal Cell Metabolism shows that intermittent fasting (IF) can improve symptoms of multiple sclerosis, and that the effects are likely due to changes in the gut microbiota.  George Weinstock and Yanjiao Zhou of The Jackson Laboratory were among the microbiome experts involved in the research.

News Reports

Can fasting improve MS symptoms?  Medical Express

Intermittent fasting may benefit people with MS  Medical News Today

 

Sept 19 – Microbiome Innovation and Investment Summit

Join us at the Microbiome Innovation and Investment Summit on September 19, 2018. Held at JAX Genomic Medicine on the UCONN Health Center campus in Farmington, CT, this conference will bring together a wide variety of people interested in microbiome research, scientific collaborations, and new company formation in this arena.

The goals of this meeting are to provide an expert overview and stimulating discussion of:

–              the current landscape in microbiome research and development

–              investment opportunities and challenges unique to this field

–              successful partnership and co-development models

–              future directions in microbiome commercialization

The Summit is being organized as part of a new initiative to link microbiome research strengths at Yale, UConn, and JAX with business development activities in the state of Connecticut. The Connecticut Microbiome Initiative seeks to promote investment and collaboration to facilitate development of microbiome-related products in biomedicine and other fields.